Carac® Has What It Takes To Be an AK Contender

	Carac®[5]	Efudex®[10]	Solaraze®[11]	Aldara™[12]
Microsponge® technology
Minimize/avoid exposure to sunlight during treatment
Concomitant sunscreen use studied
Duration of AK therapy	Up to 4 weeks	2-4 weeks	60-90 days	16 weeks
Dosage and administration	Once daily	Twice daily	Twice daily	Twice weekly
*WAC Cost†**	30-g tube $96.78	25-g tube $92.74 40-g tube $144.10	50-g tube $106.03 100-g tube $178.36	1 unit of 12 packs (3 grams) $152.85

* Wholesale acquisition cost. Comparison based on published lists of prices charged to wholesalers by manufacturers, and does not include discounts, rebates, charge backs, or other terms that may reduce the sale price to wholesalers and does not reflect actual prices paid by pharmacies or consumers.

† Medi-Span Price-Chek PC; Drug Information Report, April 6, 2005.

Efudex® is a registered trademark of Valeant Pharmaceuticals International.
Solaraze® is a registered trademark of Bioglan Pharmaceuticals Company.
Aldara™ is a trademark of the 3M Company.
Microsponge® is a registered trademark of Cardinal Health, Inc. or one of its subsidiaries.

Carac® is indicated for the topical treatment of multiple actinic or solar keratoses of the face and anterior scalp.

IMPORTANT SAFETY INFORMATION

Carac® is contraindicated in women who are or may become pregnant, in patients with dihydropyrimidine dehydrogenase (DPD) enzyme deficiency, and in patients with known hypersensitivity to any of its components. In clinical trials, the most common drug-related adverse event was application site reaction (94.6%), which included: erythema, dryness, burning, erosion, pain, and edema. Some patients also experienced eye irritation (5.4%), including stinging and burning.

For more information, please see Full Prescribing Information for Carac®.